Seedlings grown from regular seed develop a proper taproot, while clones root sideways from the stem, and outdoors in real soil that difference shows up as drought tolerance and a sturdier plant. It is one reason old school outdoor growers keep planting seed rather than cuttings every spring. Root development comparisons between seed and clone starts are shown with photos on https://breederregularseeds.com, and the gap after eight weeks is bigger than I expected. Indoors in pots it matters much less.